pensyarah universiti
institut biologi molekul perubatan ukm (umbi)
ezanee.azlina.mohamad.hanif@ppukm.ukm.edu.my
Biografi/ Biography :
Dr. Ezanee received her first degree in University Malaya (Genetics & Molecular Biology), then carried on her passion in science by enrolling as a full-time Master student in the Faculty of Medicine, UKM. Her research then looking into chromosomal aberrations in thyroid neoplasms and was exposed in several molecular cytogenetic techniques (CGH, array-CGH) and BRCA1/ BRCA2 mutation detection in breast cancer (PCR, sequencing). Immediately after, Dr Ezanee joined as a tutor in UKM Medical Molecular Biology Institute (UMBI) (2008), then converted her post to Young research fellow (2009) upon receiving her Master degree (MMed.Sc. Pathology). In 2008-2012, she was involved in several projects such as the Genotyping XMEs in breast and cervical cancer, a genome-wide methylation analysis of breast and colorectal cancers and Diabetic GWAS, all utilising the microarray applications. She was involved in the Lab Accreditation MS ISO/IEC: 17025 as Technical Manager (2009-2011). In 2012, she pursued her Ph.D degree in Centre for Cancer Research and Cell Biology, Queen’s University Belfast, UK where she conducted research studying the underlying molecular mechanisms in driving poor prognosis in triple negative breast cancer (TNBC). In the UK, she was also the vice-president for the Malaysian Postgraduate in Northern Ireland (MyPNI) taking parts in group knowledge sharing and charity activities. She was conferred her Ph.D (Medicine) in 2017, a year after her viva voce. Upon returning, Dr Ezanee is actively applying for research grants and succeeded to obtain 3 research grants in triple negative breast cancer as principle investigator. She is also a co-researcher for 6 other projects related to her field and expertise. She is also actively involved in MS ISO/IEC 17025:2017 as Approved Signatory for HLA B*1502 genotyping in epilepsy and was part of the national emergency COVID-19 task force as Approved signatory. Dr Ezanee now has six students under her supervision both as main (2) and co-supervisor (4).
chin siok fong;ezanee azlina binti mohamad hanif;nor adzimah binti johdi. (2024). elucidating lysosomal autophagy mechanism in lrg1-mediated colorectal cancer. - . .
lim sm, mohamad hanif ea, chin s-f. (2023). lrg1 induces lysosomal autophagy via dysregulation of the mtor pathway. - medicine & health. 80.
nur afifah mursyida zaujan, mohd razif shahril, suzana shahar, ezanee azlina mohamad hanif, azizi abdullah, rohaizak muhammad, razinah sharif, ponnusamy subramaniam, michael fenech. (2023). breast cancer survivors are more physically active compared to healthy women: preliminary findings from c*star (cancer survivors trajectories of aging research) study. - maso scientific conference on obesity 2023. 101.
mohd ikhwan ismail, afreena afiqah azman, mohd izwan yusof, fazleen haslinda mh, ezanee azlina mh. (2023). metabolomic fingerprinting and footprinting analyses on tnbc sh-tincr cell lines. - medicine & health. 62.
muhammad nur adam hatta; ezanee azlina mohamad hanif; siok-fong chin; teck yew low; hui-min neoh. (2023). parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line. - bioscience reports. 1-13.
lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab. (2022). a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers. - internation journal of molecular sciences. 1-16.
shing cheng tan, teck yew low, ezanee azlina mohamad hanif, mohamad ayub khan sharzehan, hamed kord-varkaneh & md asiful islam. (2021). the rs9340799 polymorphism of the estrogen receptor alpha (esr1) gene and its association with breast cancer susceptibility. - scientific reports. 18619.
muhammad nur adam hatta, ezanee azlina mohamad hanif, siok-fong chin, hui-min neoh. (2021). pathogens and carcinogenesis: a review. - biology. 1-22.
su min lim, ezanee azlina mohamad hanif, siok-fong chin. (2021). is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect. - cell and bioscience. 1-13.
su min lim, ezanee azlina mohamad hanif, siok-fong chin. (2020). modulation of leucine-rich-alpha-2-glycoprotein 1 (lrg1) promotes the survival of low-grade colorectal cancer via suppression of autophagy but not in high-grade cancer. - gut. A22.
afreena afiqah azman, chin siok fong, nor fadilah rajab, reena rahayu md zin, nurul nadiah ahmad daud, ezanee azlina mohamad hanif. (2023). the potential roles of lncrna tincr in triple negative breast cancer. - molecular biology reports. 7909-7917.
muhammad nur adam hatta; ezanee azlina mohamad hanif; siok-fong chin; teck yew low; hui-min neoh. (2023). parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line. - bioscience reports. 1-13.
nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j. (2021). covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital. - journal of infection in developing countries. 1816-1824.
mohd. firdaus che mat, ezanee azlina mohamad hanif, nor azian abdul murad, kamariah ibrahim, roslan harun, rahman jamal. (2021). silencing of zfp36l2 increases sensitivity to temozolomide through g2/m cell cycle arrest and bax mediated apoptosis in gbm cells. - molecular biology reports. 1493-1503.
ezanee azlina mohamad hanif. (2019). dysregulation of non-histone molecule mir205 and lrg1 post-transcriptional de-regulation by setd1a in triple negative breast cancer.. - molecular biology reports. 6617-6624.
muhammad nur adam hatta; ezanee azlina mohamad hanif; siok-fong chin; teck yew low; hui-min neoh. (2023). parvimonas micra infection enhances proliferation, wound healing, and inflammation of a colorectal cancer cell line. - bioscience reports. 1-13.
afreena afiqah azman, chin siok fong, nor fadilah rajab, reena rahayu md zin, nurul nadiah ahmad daud, ezanee azlina mohamad hanif. (2023). the potential roles of lncrna tincr in triple negative breast cancer. - molecular biology reports. 7909-7917.
lishantini pearanpan,fariza juliana nordin,ee ling siew ,endang kumolosasi,ezanee azlina mohamad hanif,siti fathiah masre,eng wee chua,hong sheng cheng,nor fadilah rajab. (2022). a cell-based systematic review on the role of annexin a1 in triple-negative breast cancers. - internation journal of molecular sciences. 1-16.
su min lim, ezanee azlina mohamad hanif, siok-fong chin. (2021). is targeting autophagy mechanism in cancer a good approach? the possible double-edge sword effect. - cell and bioscience. 1-13.
nor azila ma, nor azian am, azmawati mn, sharifah azura s, petrick p, najma k, mohd rohaizat h, norfazilah a, anita s, hanita o, tuti ningseh md, nurul syakima am, ezanee azlina, siti aishah, nurul syeefa', abdul rashid, abdul halim, hanafiah hr, rahman j. (2021). covid-19 in malaysia: exposure assessment and prevention practices among healthcare workers at a teaching hospital. - journal of infection in developing countries. 1816-1824.
kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu. (2020). drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies. - . 17.
ezanee azlina mohamad hanif. (2020). kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid. - . 74.
kha wai hon, norahayu othman, ezanee azlina mohamad hanif, siti nurmi nasir, nur syahada abd razak, rahman jamal, nadiah abu. (2020). drug resistance in colorectal cancer: molecular mechanisms and therapeutic strategies. - . 17.
siti aishah sulaiman, nor azian abdul murad, ezanee azlina mohamad hanif, nadiah abu, and rahman jamal. (2018). circular rna: biogenesis and function. - . 370.
ezanee azlina mohamad hanif. (2020). kromosom dan mekanisme gen: keupayaan diagnostik dalam pembentukan lesi/neoplasma tiroid. - . 74.
chin siok fong;ezanee azlina binti mohamad hanif;nor adzimah binti johdi. (2024). elucidating lysosomal autophagy mechanism in lrg1-mediated colorectal cancer. - . .
nur afifah mursyida zaujan, mohd razif shahril, suzana shahar, ezanee azlina mohamad hanif, azizi abdullah, rohaizak muhammad, razinah sharif, ponnusamy subramaniam, michael fenech. (2023). breast cancer survivors are more physically active compared to healthy women: preliminary findings from c*star (cancer survivors trajectories of aging research) study. - maso scientific conference on obesity 2023. 101.
nor azian abdul murad, ezanee azlina mohamad hanif, siti aishah sulaiman, & razinah sharif. (2022). gamifikasi kaedah genotiping 1.0: prinsip teknologi dan analisis asas. - knovasi 2022. 1.
afreena afiqah a, nurul nadiah ad, chin siok fong, norfadilah r, reena rahayu mz, rohaizak m, norlia a, nani harlina ml ezanee azlina mh*. (2022). elucidating the transcriptional regulation and chemosensitivity efficacy of terminal differentiation induced non-coding rna (tincr) driver regulator in triple-negative breast cancer (tnbc). - 2nd macr international scientific conference 2022. 30.
neoh hui min;a. rahman bin a. jamal;shamsul azhar bin shah;ezanee azlina binti mohamad hanif;chin siok fong;nadiah binti abu;low teck yew. (2022). elucidating the roles of two oral microbiota, parvimonas micra and peptostreptococcus stomatis in colorectal cancer pathology . - . .