pegawai penyelidik
jabatan patologi
nurmayasabrina@ukm.edu.my
Biografi/ Biography :
Nur Maya Sabrina Tizen Laim ialah Pegawai Penyelidik di Jabatan Patologi, Fakulti Perubatan, Universiti Kebangsaan Malaysia (UKM) dan telah berkhidmat sejak tahun 2009. Beliau memperoleh Ijazah Sarjana Muda Sains dengan Kepujian dalam bidang Genetik dari UKM pada tahun 2007 dan seterusnya menamatkan pengajian Sarjana Sains Perubatan dalam bidang Patologi dari institusi yang sama pada tahun 2021.
Dengan lebih daripada satu dekad pengalaman dalam bidang patologi, penyelidikan beliau banyak memberi tumpuan kepada perubatan makmal khususnya dalam bidang histologi, histopatologi dan genetik molekul. Bidang penyelidikannya merangkumi pelbagai jenis kanser seperti limfoma, kanser payudara, kanser kolorektal serta tumor pepejal yang lain.
Beliau telah terlibat secara aktif dalam pelbagai projek penyelidikan dan kolaborasi, menyumbang kepada penerbitan jurnal yang mengkaji penanda biomolekul kanser, persekitaran mikro tumor, serta aplikasi teknik seperti imunohistokimia (IHC), imunofluoresens (IF), dan tisu mikroarray (TMA). Hasil penyelidikannya sering menjurus ke arah penggabungan antara diagnostik klinikal dan penyelidikan translasi, dengan minat khas terhadap penggunaan kaedah pewarnaan lanjutan dan pemprofilan molekul bagi meningkatkan ketepatan diagnosis dan penilaian prognosis.
Dalam beberapa tahun kebelakangan ini, beliau turut menunjukkan minat yang semakin mendalam terhadap patologi digital, khususnya dalam potensinya untuk analisis penanda kanser dan sokongan diagnostik berasaskan imej, sejajar dengan perkembangan semasa dalam perubatan presisi. Sumbangan beliau mencerminkan komitmen tinggi dalam memajukan penyelidikan kanser melalui pendekatan makmal yang inovatif dan praktikal.
Nur Maya Sabrina Tizen Laim is a Research Officer at the Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), where she has served since 2009. She holds a Bachelor of Science with Honours in Genetics from UKM (2007) and earned her Master of Medical Science in Pathology from the same institution in 2021.
With over a decade of experience in the field of pathology, her research has centered on laboratory medicine—particularly in the areas of histology, histopathology, and molecular genetics. Her work has contributed significantly to the understanding of various malignancies, with a primary focus on lymphoma, breast cancer, colorectal cancer, and other solid tumors.
She has been actively involved in numerous research projects and collaborations, contributing to peer-reviewed publications that explore cancer biomarkers, tumour microenvironment, immunohistochemistry (IHC), immunofluorescence (IF), and tissue microarray (TMA) techniques. Her work often bridges the gap between clinical diagnostics and translational research, with a special interest in the application of advanced staining methods and molecular profiling to improve diagnostic accuracy and prognostic evaluation.
In recent years, she has developed a growing interest in digital pathology, especially in its potential application for cancer biomarker analysis and image-based diagnostic support, aligning with current trends in precision medicine. Her contributions reflect a strong commitment to advancing cancer research through innovative yet practical laboratory approaches.
wan alina khadijah, ramlah mohamed ibrahim, raja zahratul azma raja sabudin, s. fadilah abdul wahid, nor rafeah tumian, azlin ithnin, lailatul hadziyah mohd pauzy, hafiza alauddin. (2025). acute basophilic leukemia in relapsed, post-transplant acute myeloid leukemia, myelodysplasia-related. - 22nd annual scientific meeting malaysian society of haematology 2025. .
ramlah mohamed ibrahim, raja zahratul azma raja sabudin, azlin ithnin, qhasmira abu hazir, nor rafeah tumian. (2025). myeloid sarcoma in chronic myelogenous leukemia: a rare complication of disease transformation. - 22nd annual scientific meeting malaysian society of haematology 2025. .
ramlah mohamed ibrahim, azlin ithnin, raja zahratul azma raja sabudin, mohd fikri bin mustapa, nor rafeah tumian, siti hawa abu amis, puan nor hidayati sardi. (2025). revolutionizing chronic myeloid leukemia monitoring: bcr-abl1 quantification comparison of digital pcr and rt-qpcr. - 22nd annual scientific meeting malaysian society of haematology 2025. .
mohd fikri mustapa, raja zahratul azma raja sabudin, qhasmira abu hazir, alia suzana asri, lailatul hadziyah mohd pauzy, c-kai loh. (2025). acute megakaryoblastic leukemia with tetrasomy 21 clone in a child with down syndrome. - 22nd annual scientific meeting malaysian society of haematology 2025. .
nur aisyah shaiful azman, azma rz, alia suzana asri, qhasmira abu hazir, raja muhammad zul hatta, noorhana sofia, ahmad nasirudin mustafa, nizmah mahani, noraesah m, norafiza mohd yassin, ezalia esa. (2025). molecular characterization of alpha thalassemia among sabah populations. - 22nd annual scientific meeting malaysian society of haematology 2025. .
hashim halim-fikri, ninie nadia zulkipli, hafiza alauddin, celeste bento, carsten w lederer5, petros kountouris, marina kleanthous, yetti hernaningsih, meow-keong thong, muhammad hamdi mahmood, norafiza mohd yasin, ezalia esa, jacques elion, domenico coviello, raja-zahratul-azma raja-sabudin, ghada el-kamah, john burn, narazah mohd yusoff, raj ramesar, bin alwi zilfalil, on behalf of the global globin network (ggn). (2024). global globin network and adopting genomic variant database requirements for thalassemia. - database-the journal of biological databases and curation. 1 - 14.
pathmanathan rajadurai, sarala ravindran, bang rom lee, suria hayati md pauzi, seow fan chiew, kean hooi teoh, navarasi s. raja gopal, mastura md yusof, cheng har yip. (2024). consensus guidelines on human epidermal growth factor receptor 2 (her2)-low testing in breast cancer in malaysia. - cancers. 1 - 19.
natasha archer, coralea stephanou, maria xenophontos, leon tshilolo, franck nzengu lukusa, sylvain fazili, obiageli e nnodu, maxwell nwegbu, ali dahiru waziri, sani awwalu, soteroula christou, irene savvidou, ann rekleiti, anna minaidou, michail d diamantidis, norafiza mohd yasin, norasmidar abdul aziz, veena selvaratnam, ezalia esa, andreas glenthoej, sophia delicou, livingstone gayus dogara, maria dimopoulou, raja sabudin, norunaluwar jalil, c-khai loh, sie-chong doris lau, bin alwi zilfalil, norsarwany mohamad, syahiran mohammad, ahmad-zafrullahafham ahmad-fakri, halim-fikri hashim, morohuntodun o. oni, antonieta lukangu, ligia alves, miguel brito, viviana giannuzzi, fedele bonifazi, kyriaki michailidou, sotiroula chatzimatthaiou, carsten lederer, petros kountouris. (2024). analysis of the pilot study of the international hemoglobinopathy research network (inherent). - blood. 1132 - 1134.
wan syahira ellani wan ahmad kammal, masturah ramli, nur maya sabrina tizen laim, muaatamarulain mustangin, azimatun noor aizuddin, nordashima abd shukor. (2022). the diagnostic utility of c4d immunohistochemistry in membranous glomerulonephritis. - histopathology. 174.
mohd fazirul mustafa, suhainizam muhamad saliluddin, sharida fakurazi, nur maya sabrina tizen laim, suria hayati md pauzi, nik hasimah nik yahya, navarasi s. raja gopal, maizaton atmadini abdullah and sandra maniam. (2021). expression of autophagy and mitophagy markers in breast cancer tissues. - frontiers in oncology. 1-12.
izzatul aliaa badaruddin, hanita othman, wan muhammad azfar wan shuaib, mohd zakie che yusof, shahifaniza othman, mohd nazrul anuar ali, ida mastura mat, munirah md mansor, azmawati mohammed nawi. (2024). navigating immune landscapes: insights from a prospective study. - asia pacific journal of public health. 806 - 809.
nurull eddayu hasbullah, raja zahratul azma raja sabudin, alia suzana asri, nurasyikin yusof, chooi fun leong, fazarina mohammed, chuan hun ding, nor rafeah tumian. (2024). marrow talaromycosis as the initial presentation in a case of burkitt lymphoma. - malaysian journal of pathology. 325 - 329.
barizah syahirah hanim, yin ping wong, geok chin tan, nordashima abd shukor. (2024). icam-1 expression is upregulated in the umbilical vein endothelial cells in acute chorioamnionitis with foetal inflammatory response. - malaysian journal of pathology. 423 - 430.
pathmanathan rajadurai, ning yi yap, seow fan chiew, reena rahayu md zin, suria hayati md pauzi, aniqah shamimi binti jaafar, azyani yahaya, lai meng looi. (2024). prevalence of programmed death-ligand 1 positivity using sp142 in patients with advanced stage triple-negative breast cancer in malaysia: a cross-sectional study. - journal of breast cancer. 1 - 10.
ramlah mohamed ibrahim, raja zahratul azma raja sabudin, noor aini anuwar, azlin ithnin, mohd fikri mustapa, sivakumar palaniapan, nor rafeah tumian. (2024). bone marrow fibrosis in a young patient with chronic myeloid leukaemia . - malaysian journal of pathology. 470 - 470.
izzatul 'aliaa badaruddin, ariff norbani, jing ya chin, ezzah sofea md said, uvarrajeswari selvarajoo, nur tihani mohammad khaidir, nurul fahmiza tumiran, raja zahratul azma, nor azlin mohamed ismail. (2024). the role of maternal serum ferritin in gestational diabetes mellitus in southeast asia. - cureus. 1 - 8.
ramlah mohamed ibrahim, raja zahratul azma raja sabudin, noor aini anuwar, azlin ithnin, mohd fikri mustapa, sivakumar palaniapan, nor rafeah tumian. (2024). bone marrow fibrosis in a young patient with chronic myeloid leukaemia . - malaysian journal of pathology. 470 - 470.
hashim halim-fikri, ninie nadia zulkipli, hafiza alauddin, celeste bento, carsten w lederer5, petros kountouris, marina kleanthous, yetti hernaningsih, meow-keong thong, muhammad hamdi mahmood, norafiza mohd yasin, ezalia esa, jacques elion, domenico coviello, raja-zahratul-azma raja-sabudin, ghada el-kamah, john burn, narazah mohd yusoff, raj ramesar, bin alwi zilfalil, on behalf of the global globin network (ggn). (2024). global globin network and adopting genomic variant database requirements for thalassemia. - database-the journal of biological databases and curation. 1 - 14.
nurull eddayu hasbullah, raja zahratul azma raja sabudin, alia suzana asri, nurasyikin yusof, chooi fun leong, fazarina mohammed, chuan hun ding, nor rafeah tumian. (2024). marrow talaromycosis as the initial presentation in a case of burkitt lymphoma. - malaysian journal of pathology. 325 - 329.
pathmanathan rajadurai, sarala ravindran, bang rom lee, suria hayati md pauzi, seow fan chiew, kean hooi teoh, navarasi s. raja gopal, mastura md yusof, cheng har yip. (2024). consensus guidelines on human epidermal growth factor receptor 2 (her2)-low testing in breast cancer in malaysia. - cancers. 1 - 19.
nur maya sabrina tizen laim. (2022). teknik aturan mikro tisu. - . 1-19.
nurwahyuna rosli, nur maya sabrina tizen laim. (2021). apa yang doktor buat dengan apendiks saya? - perjalanan tisu dari meja pembedahan ke pentas mikroskop. - majalah patologi. 1-6.
husyairi harunarashid, nurul saadah ahmad, nur maya sabrina tizen laim, nurazilah mohamed sallehulldin. (2021). menggembeling kekuatan bakat saintifik dan penyelidikan melalui pemerkasaan deskripsi tugas skim q (ro) di makmal,pusat kecemerlangan dan hospital pengajar milik institusi pengajian tinggi awam. - . 1-18.
tan geok chin, nur maya sabrina tizen laim. (2018). mikrorna dan isomirs: kecil tetapi berperanan besar. - majalah patologi. .
geok chin tan, sabrina florence chandramaya. (2017). plasenta: teman si bayi. - majalah patologi. 1-3.
wan alina khadijah, ramlah mohamed ibrahim, raja zahratul azma raja sabudin, s. fadilah abdul wahid, nor rafeah tumian, azlin ithnin, lailatul hadziyah mohd pauzy, hafiza alauddin. (2025). acute basophilic leukemia in relapsed, post-transplant acute myeloid leukemia, myelodysplasia-related. - 22nd annual scientific meeting malaysian society of haematology 2025. .
ramlah mohamed ibrahim, raja zahratul azma raja sabudin, azlin ithnin, qhasmira abu hazir, nor rafeah tumian. (2025). myeloid sarcoma in chronic myelogenous leukemia: a rare complication of disease transformation. - 22nd annual scientific meeting malaysian society of haematology 2025. .
ramlah mohamed ibrahim, azlin ithnin, raja zahratul azma raja sabudin, mohd fikri bin mustapa, nor rafeah tumian, siti hawa abu amis, puan nor hidayati sardi. (2025). revolutionizing chronic myeloid leukemia monitoring: bcr-abl1 quantification comparison of digital pcr and rt-qpcr. - 22nd annual scientific meeting malaysian society of haematology 2025. .
mohd fikri mustapa, raja zahratul azma raja sabudin, qhasmira abu hazir, alia suzana asri, lailatul hadziyah mohd pauzy, c-kai loh. (2025). acute megakaryoblastic leukemia with tetrasomy 21 clone in a child with down syndrome. - 22nd annual scientific meeting malaysian society of haematology 2025. .
nur aisyah shaiful azman, azma rz, alia suzana asri, qhasmira abu hazir, raja muhammad zul hatta, noorhana sofia, ahmad nasirudin mustafa, nizmah mahani, noraesah m, norafiza mohd yassin, ezalia esa. (2025). molecular characterization of alpha thalassemia among sabah populations. - 22nd annual scientific meeting malaysian society of haematology 2025. .