prof. madya dr. ng chyan leong

pensyarah universiti

institut biologi sistem (inbiosis)

 clng@ukm.edu.my



   Kluster Kepakaran/ Cluster of Expertise :
  • Sumber Lestari, Alam Sekitar dan Kehidupan Pintar,



  •    Biografi/ Biography :

  • Dr. Ng Chyan Leong is a senior research fellow in the Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia. He graduated from the Universiti Putra Malaysia where he earned a Bachelor in Biotechnology and Master in Molecular Biology. He completed his PhD in structural biology at the York Structural Biology Laboratory, University of York, UK. He then worked as postdoctoral fellow at the Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK. His researches focus on the structural and functional studies of biologically important macromolecules including secondary metabolites biosynthesis enzymes, hypothetical proteins in human and pathogenic bacteria.

  • foo pei ya, nazalan najimudin, pravin kumran nyanasegran, ng chyan leong .  (2025).  pencerapan dan analisis fenomena pembunuhan klonal escherichia coli atas medium pertumbuhan minimum tertakrif berbanding dengan medium kaya.  - sains malaysiana.  1713 - 1723. 

     

    jia rong tey, siti fatimah, maizom hassan, anusha nair, chyan leong ng.  (2025).  structural and functional analysis of plant oil-body lipase eglip1 from elaeis guineensis.  - proteins: structure, function, and bioinformatics.  1921 - 1934. 

     

    domniq pavitiren arokiam, mona fatin syazwanee mohamed ghazali, izwan bharudin, shazilah kamaruddin, nor azlan nor muhammad, chyan leong ng, sanjib bhakta, abdul munir abdul murad and doris huai xia quay.  (2025).  expression, purification and biochemical characterisation of rv3368, an fmn-dependent nitroreductase from mycobacterium tuberculosis h37rv.  - simposium biologi kebangsaan ke-11. 

     

    han-ni booi, li-yin pang, mei-kee lee, shin-yee fung, chyan-leong ng, szu-ting ng, chon-seng tan, cin kong, kuan-hon lim, richard roberts, kang-nee ting.  (2025).  evidence to support cultivated fruiting body of ophiocordyceps sinensis (ascomycota)’s role in relaxing airway smooth muscle .  - journal of ethnopharmacology.  1 - 10. 

     

    syed abuthakir mohamed husain, su datt lam, nor azlan nor muhammad, mohd firdaus-raih, jayanthi nagappan, rozana rosli, kuang-lim chan, eng-ti leslie low, chyan leong ng.  (2025).  integrative in silico approach in structure guided functional annotation of hypothetical proteins in elaeis guineensis.  - international conference of biochemistry, molecular biology & laboratory medicine 2025 (icbmblm 2025). 

     

    jia rong tey, siti fatimah, maizom hassan, anusha nair, chyan leong ng.  (2025).  structural and functional analysis of plant oil-body lipase eglip1 from elaeis guineensis.  - proteins: structure, function, and bioinformatics.  1921 - 1934. 

     

    han-ni booi, li-yin pang, mei-kee lee, shin-yee fung, chyan-leong ng, szu-ting ng, chon-seng tan, cin kong, kuan-hon lim, richard roberts, kang-nee ting.  (2025).  evidence to support cultivated fruiting body of ophiocordyceps sinensis (ascomycota)’s role in relaxing airway smooth muscle .  - journal of ethnopharmacology.  1 - 10. 

     

    neng-yao goh, yeannie hui-yeng yap, chyan leong ng, boon-hong kong, szu-ting ng, chon-seng tan, muhammad fazril mohamad razif, shin-yee fung.  (2024).  water-soluble compounds from lignosus rhinocerus tm02 (xlr) modulate ace2 activity and inhibit its interaction with sars-cov-2 spike-protein.  - food bioscience.  1-15. 

     

    alice li-wen kiang, shu-san loo, mohd-noor mat-isa, chyan-leong ng, damer p. blake, kiew-lian wan.  (2024).  insights into genomic sequence diversity of the sag surface antigen superfamily in geographically diverse eimeria tenella isolates.  - scientific reports.  1 - 11. 

     

    rubashiny veeramohan, arief izzairy zamani, kamalrul azlan azizan, hoe-han goh, wan mohd aizat, mohd fauzi abd razak, nur sabrina mohd yusof, sharif mahsufi mansor, syarul nataqain baharum, chyan leong ng.  (2023).  comparative metabolomics analysis reveals alkaloid repertoires in young and mature mitragyna speciosa (korth.) havil. leaves.  - plos one.  1-24. 

     

    foo pei ya, nazalan najimudin, pravin kumran nyanasegran, ng chyan leong .  (2025).  pencerapan dan analisis fenomena pembunuhan klonal escherichia coli atas medium pertumbuhan minimum tertakrif berbanding dengan medium kaya.  - sains malaysiana.  1713 - 1723. 

     

    nurul fadzillah fadhar, pravin kumran nyanasegran, mohd firdaus-raih, sheila nathan, mohd anuar jonet, chyan leong ng.  (2024).  protein expression, purification, crystallization and crystallographic studies of bpsl0741 from burkholderia pseudomallei.  - structural biology communications.  263 - 268. 

     

    norliana-izzati mr, lee ct, fauziah a, zunoliza a, ling sk, mohd-hafidz-hadi a, ng kks, ng ch, tnah lh, ng cl, goh h-h, lee sl.  (2024).  hplc-pda method for the quantification of mitragynine in fresh kratom (mitragyna speciosa) leaf.  - journal of tropical forest science.  434 - 443. 

     

    asqwin uthaya kumar, muhammad ahmad zan, chyan-leong ng, sylvia chieng, sheila nathan.  (2024).  diabetes and infectious diseases with a focus on melioidosis.  - current microbiology.  1-14. 

     

    pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng.  (2023).  biofilm signaling, composition and regulation in burkholderia pseudomallei.  - journal of microbiology and biotechnology.  15-27. 

     

    foo pei ya, nazalan najimudin, pravin kumran nyanasegran, ng chyan leong .  (2025).  pencerapan dan analisis fenomena pembunuhan klonal escherichia coli atas medium pertumbuhan minimum tertakrif berbanding dengan medium kaya.  - sains malaysiana.  1713 - 1723. 

     

    jia rong tey, siti fatimah, maizom hassan, anusha nair, chyan leong ng.  (2025).  structural and functional analysis of plant oil-body lipase eglip1 from elaeis guineensis.  - proteins: structure, function, and bioinformatics.  1921 - 1934. 

     

    han-ni booi, neng-yao goh, mei-kee lee, chyan-leong ng, szu-ting ng, chon-seng tan, kuan-hon lim, richard roberts, shin-yee fung, kang-nee ting.  (2025).  metabolomic data on molecular weight fractions of the cultivated fruiting body of ophiocordyceps sinensis and their pharmacological effects on airway tissues.  - data in brief.  1 - 8. 

     

    han-ni booi, li-yin pang, mei-kee lee, shin-yee fung, chyan-leong ng, szu-ting ng, chon-seng tan, cin kong, kuan-hon lim, richard roberts, kang-nee ting.  (2025).  evidence to support cultivated fruiting body of ophiocordyceps sinensis (ascomycota)’s role in relaxing airway smooth muscle .  - journal of ethnopharmacology.  1 - 10. 

     

    nurul fadzillah fadhar, pravin kumran nyanasegran, mohd firdaus-raih, sheila nathan, mohd anuar jonet, chyan leong ng.  (2024).  protein expression, purification, crystallization and crystallographic studies of bpsl0741 from burkholderia pseudomallei.  - structural biology communications.  263 - 268. 

     

    shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih.  (2019).  structural genomics.  - 722-728. 

     

    chyan leong ng & mohd firdaus-raih.  (2019).  applications of ribosomal rna sequence and structure analysis for extracting evolutionary and functional insight.  - 554-567. 

     

    hoe han goh, chyan leong ng, kok keong loke.  (2018).  functional genomics.  - advances in experimental medicine and b.  11-30. 

     

    foo pei ya, nazalan najimudin, pravin kumran nyanasegran, ng chyan leong .  (2025).  pencerapan dan analisis fenomena pembunuhan klonal escherichia coli atas medium pertumbuhan minimum tertakrif berbanding dengan medium kaya.  - sains malaysiana.  1713 - 1723. 

     

    rubashiny veeramohan, syarul nataqain baharum, ng chyan leong.  (2024).  merungkai tapak jalan biosintesis alkaloid indol mitragyna speciosa melalui pendekatan intergrasi omik.  -

     

    izyanti binti ibrahim;zamri bin zainal;aidil bin abdul hamid;ng chyan leong.  (2021).  peranan enzim malik di dalam proses pengumpulan lipid oleh kulat oleaginus cunninghamella bainieri 2a1.  -

     

    juwairiah remali, noraziah mohamad zin, chyan leong ng, wan m. aizat & john j.l tiong.  (2019).  fenazin sebagai potensi antibiotik baru daripada streptomyces kebangsaanensis.  - sains malaysiana.  543-553. 

     

    mahasakthy vijeyasri satyaveanthan, ng chyan leong, alias awang, and bimo ario tejo, maizom hassan.  (2018).  coklat: pertarungan menyelamatkan makanan kegemaran dunia.  - majalah impak universiti kebangsaan malaysia. 

     

    syed abuthakir mohamed husain, su datt lam, nor azlan nor muhammad, mohd firdaus-raih, jayanthi nagappan, rozana rosli, kuang-lim chan, eng-ti leslie low, chyan leong ng.  (2025).  integrative in silico approach in structure guided functional annotation of hypothetical proteins in elaeis guineensis.  - international conference of biochemistry, molecular biology & laboratory medicine 2025 (icbmblm 2025). 

     

    lai ying hui, ng chyan leong, maizah mohamed yatim, noor zaitulakma binti md zain, tsen min tze.  (2025).  characterization of pathogenic escherichia coli bacteriophage .  - international conference of biochemistry, molecular biology & laboratory medicine 2025 (icbmblm 2025). 

     

    ng chyan leong .  (2025).  exploring hypothetical protein revealspotential new enzyme subclass.  - ribo25 symposium. 

     

    domniq pavitiren arokiam, mona fatin syazwanee mohamed ghazali, izwan bharudin, shazilah kamaruddin, nor azlan nor muhammad, chyan leong ng, sanjib bhakta, abdul munir abdul murad and doris huai xia quay.  (2025).  expression, purification and biochemical characterisation of rv3368, an fmn-dependent nitroreductase from mycobacterium tuberculosis h37rv.  - simposium biologi kebangsaan ke-11. 

     

    mohamed husain syed abuthakir, su datt lam, mohd firdaus-raih, sheila nathan, nor azlan nor muhammad, chyan leong ng.  (2025).  structure-guided functional annotation of hypothetical proteins of burkholderia pseudomallei using in silico approaches.  - 31st faobmb conference & 2025 ksbmb international conference. 

     

    BIOCHEMISTRY :PURE AND APPLIED SCIENCES
    Structural Biology
    Pengalaman / Experience : 16 tahun/years(s)

    BIOCHEMISTRY :PURE AND APPLIED SCIENCES
    X-Ray Crystallography for macromolecules, Protein structure studies
    Pengalaman / Experience : tahun/years(s)

    BIOTECHNOLOGY :PURE AND APPLIED SCIENCES
    Systems Biology
    Pengalaman / Experience : 12 tahun/years(s)