Kluster Kepakaran/ Cluster of Expertise :
Kesihatan dan Perubatan Termaju,
Biografi/ Biography :
Assoc. Prof. Dr. Goon Jo Aan earned her PhD from UKM in 2007 and has been a dedicated academic and researcher at the university ever since. She was promoted to Associate Professor in 2016 and served as Head of the Department of Biochemistry from 2018 to 2025. Her research focuses on the role of antioxidant supplements in preventing age-related disorders and promoting healthspan. She also uses Caenorhabditis elegans as a model organism to explore the molecular mechanisms of aging. Dr. Goon has led various national and international research projects, securing over RM5 million in funding. She has published more than 52 peer-reviewed papers and successfully supervised numerous PhD and MSc students. She has received multiple awards for research and education and is actively involved as an external examiner and accreditation assessor. She was instrumental in establishing the Joint PhD Degree in Medical Science between UKM and Shiga University of Medical Science, Japan.
acharaporn issuriya, palika wetchakul, surasak limsuwan, siriwimol jiwpraditkul, patcharawalai jaisamut, thammarat kaewmanee, jo aan goon, sineenart sanpinit. (2025). anti-hyperglycemic and toxicological effects of a traditional polyherbal formulation, athamathurot, used at bantakhun hospital, thailand. - journal of agriculture and food research. 1 - 12.
nor amira nabila amir razak, jo aan goon, wan zurinah wan ngah, suzana makpol, mohd hanafi ahmad damanhuri, nor faeizah ibrahim, nur fathiah abdul sani, nuraqila mohd murshid, anis faqihah mohd azizan, kok yong chin, amilia aminuddin, mohd heikal mohd yunus, munirah md mansor , juvenia rui en neo, wei ney yap, hsieu yen loong, yee wei ung. (2025). effectiveness of tocotrienol-rich fraction in older adults: protocol for a randomized, double-blind, placebo-controlled trial. - jmir research protocols. 1 - 18.
acharaporn issuriya, sineenart sanpinit, surasak limsuwan, jo aan goon and palika wetchakul . (2025). in vitro antioxidant properties of mitratonic remedy in tea form and in vivo protection against methanol-induced oxidative stress in wistar rats. - scientifica. 1 - 12.
mohd khairul zain nh, mohd azli sna, makpol s, wan ngah wz, goon ja, damanhuri h, abdul karim n, chin ky, tan jk, aminuddin a, md mansor m, mohd yunus mh, ung yw, yap wn, loong mhy, abdul sani nf. (2025). effects of tocotrienol-rich fraction on dietary intake and body composition: interim findings from a double-blind randomised controlled trial. - 27th medical & health research week 'upholding credibility in an evolving research landscape'. .
jo aan goon, xin yee tan, siti nurliyana mohd yazid,abdulhakeem bello, muhammad aiman husnun, jazween loo, geetha gunasekaran, fazaine zakaria, kok yong chin. (2025). effect of dietary restriction on the healthspan of caenorhabditis elegans. - medicine & health. 754 - 763.
yuezhi zhu, jen kit tan, jia liu and jo aan goon. (2024). roles of traditional and next-generation probiotics on non-alcoholic fatty liver disease (nafld) and non-alcoholic steatohepatitis (nash): a systematic review and network meta-analysis. - antioxidants. 1-20.
palika wetchakula, soiphet net-anonga, jo aan goon, sineenart sanpinita. (2024). anti-oxidative stress and gastroprotective effect of tri-tharn-thip tea against ethanol-induced gastric ulcer in rats. - south african journal of botany. 130-136.
jazween loo, geetha gunasekaran, jen kit tan, jo aan goon . (2024). elucidating the effective age for dietary restriction and the key metabolites involved. - experimental gerontology. 1 - 12.
jazween loo, muhammad arif fikri shah bana, jen kit tan, jo aan goon. (2023). effect of dietary restriction on health span in caenorhabditis elegans: a systematic review. - experimental gerontology. 1-7.
kartthigeen tamel selvan, jo aan goon, suzana makpol, jen kit tan. (2023). therapeutic potentials of microalgae and their bioactive compounds on diabetes mellitus. - marine drugs. 1-36.
tan tzer sien, muhammad firdaus sathik rahman, siti sara ismail, nur najihah mohamad, ahmad hazim mustaffa, geetha gunasekaran, siti bazilah zulkefli & goon jo aan. (2021). effect of the tocotrienol-rich fraction (trf) on the healthspan of caenorhabditis elegans. - sains malaysiana. 429-436.
nurul ain mohamad kamal, jiann lin loo, jo aan goon, hanafi ahmad damanhuri, shalisah sharip, suriati mohd saini, jemaima che hamzah, lai fong chan. (2019). oxidative stress: biomarkers in bipolar disorder with suicidal behavior: a systematic review. - journal of pharmaceutical negative results. 6-15.
siti madiani abdul ghani, jo aan goon, nor helwa ezzah nor azman, siti nor asyikin zakaria, zalina hamid, wan zurinah wan ngah. (2019). comparing the effects of vitamin e tocotrienol-rich-fraction supplementation and a-tocopherol supplementation on gene expression in healthy older adults. - clinics. 1-13.
jaclyn tan ai chin, geetha gunasekaran, mohd hanafi ahmad damanhuri, chan lai fong, loo jiann lin, goon jo aan. (2019). oxidative status in bipolar disorder (bd) and its correlation with age, gender and body masss index (bmi). - sains malaysiana. 1083-1095.
goon jo aan, noralisa abdul karim, mohd shahril aszrin zainudin, suzana makpol. (2019). tocotrienol rich fraction modulates genes expression in oxidative stress-induced caenorhabditis e legans. - bangladesh journal of medical science. 711-721.
nor amira nabila amir razak, jo aan goon, wan zurinah wan ngah, suzana makpol, mohd hanafi ahmad damanhuri, nor faeizah ibrahim, nur fathiah abdul sani, nuraqila mohd murshid, anis faqihah mohd azizan, kok yong chin, amilia aminuddin, mohd heikal mohd yunus, munirah md mansor , juvenia rui en neo, wei ney yap, hsieu yen loong, yee wei ung. (2025). effectiveness of tocotrienol-rich fraction in older adults: protocol for a randomized, double-blind, placebo-controlled trial. - jmir research protocols. 1 - 18.
acharaporn issuriya, palika wetchakul, surasak limsuwan, siriwimol jiwpraditkul, patcharawalai jaisamut, thammarat kaewmanee, jo aan goon, sineenart sanpinit. (2025). anti-hyperglycemic and toxicological effects of a traditional polyherbal formulation, athamathurot, used at bantakhun hospital, thailand. - journal of agriculture and food research. 1 - 12.
acharaporn issuriya, sineenart sanpinit, surasak limsuwan, jo aan goon and palika wetchakul . (2025). in vitro antioxidant properties of mitratonic remedy in tea form and in vivo protection against methanol-induced oxidative stress in wistar rats. - scientifica. 1 - 12.
yuezhi zhu, jen kit tan, jia liu and jo aan goon. (2024). roles of traditional and next-generation probiotics on non-alcoholic fatty liver disease (nafld) and non-alcoholic steatohepatitis (nash): a systematic review and network meta-analysis. - antioxidants. 1-20.
kartthigeen tamel selvan, jo aan goon, suzana makpol, jen kit tan. (2024). stepwise optimization of rt-qpcr for analysis of hepatic lipid metabolism in mafld-induced hepg2 cell model. - asia-pacific journal of molecular biology and biotechnology. 79 - 79.
goon jo aan, zakiah jubri, mohd hanafi ahmad damanhuri, wan nurzulaikha wan nasri. (2022). prinsip dan kaedah pengukuran vitamin antioksidan menggunakan high performance liquid chromatography (hplc). - . 100-114.
goon jo aan. (2022). prinsip dan kaedah menguji ketahanan tekanan oksidatif caenorhabditis elegans. - . 90-99.
goon jo aan. (2022). prinsip dan kaedah pengukuran aktiviti enzim antioksidan. - . 19-30.
goon jo aan, zakiah jubri. (2022). bab 1: status oksidatif. - . 15-18.
goon jo aan. (2023). puasa berselang jadi anti-penuaan?. - mingguan malaysia. 1.
goon jo aan, zakiah jubri, mohd hanafi ahmad damanhuri, wan nurzulaikha wan nasri. (2022). prinsip dan kaedah pengukuran vitamin antioksidan menggunakan high performance liquid chromatography (hplc). - . 100-114.
goon jo aan. (2022). prinsip dan kaedah menguji ketahanan tekanan oksidatif caenorhabditis elegans. - . 90-99.
goon jo aan. (2022). prinsip dan kaedah pengukuran aktiviti enzim antioksidan. - . 19-30.
goon jo aan, suzana makpol, zakiah jubri. (2022). panduan pengukuran status oksidatif. - . 1.
goon jo aan, amira nabila amir razak, suzana makpol, nor faeizah ibrahim, nur fathiah sani, amilia aminuddin, mohd heikal mohd yunus, chin kok yong, munirah mansor, wan zurinah wan ngah. (2025). second interim report for clinical trial: a randomized, double-blinded, placebo-controlled study to evaluate the efficacy of oral supplementation of tocotrienol rich fraction (davoslife e3 complete). - . .
mohd khairul zain nh, mohd azli sna, makpol s, wan ngah wz, goon ja, damanhuri h, abdul karim n, chin ky, tan jk, aminuddin a, md mansor m, mohd yunus mh, ung yw, yap wn, loong mhy, abdul sani nf. (2025). effects of tocotrienol-rich fraction on dietary intake and body composition: interim findings from a double-blind randomised controlled trial. - 27th medical & health research week 'upholding credibility in an evolving research landscape'. .
yuezhi zhu, jen kit tan, jo aan goon. (2024). impact of cuproptosis and m6a-associated lncrnas on the lipidomic pathway in high-risk hepatocellular carcinoma patients. - third international lipidomics society conference & smart symposium on structurallipidomics. .
jen kit tan, kartthigeen tamel selvan, ayaka nakashima, kengo suzuki, yu inaba, jo aan goon, hiroshi tsugawa, suzana makpol. (2024). lipidomics profiling of nafld cells treated with aurantiochytrium sp. extract. - third international lipidomics society conference & smart symposium on structurallipidomics. .
jen kit tan, kartthigeen tamel selvan, ayaka nakashima, kengo suzuki, yu inaba, jo aan goon, hiroshi tsugawa, suzana makpol. (2024). lipid-lowering effects of microalgae extracts on a cell model of nonalcoholic fatty liver disease (nafld). - global algae summit 2024. .
| Geran / Grant | Kolaborator / Collaborator | Status |
|---|---|---|
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | malaysian palm oil board | 69.8% (2022-11-29 sehingga 2027-01-30) |
| TOCOTRIENOL AS A SENOLYTIC AGENT: A PHASE 2 CLINICAL TRIAL | davos life science sdn bhd | 69.8% (2022-11-29 sehingga 2027-01-30) |
| ELUCIDATING THE ROLE OF MIRNA 129 ON NON-ALCOHOLIC FATTY LIVER DISEASE DRIVEN HEPATOCELLULAR CARCINOMA. | heze huiren chinese medicine hospital | 90.5% (2022-08-01 sehingga 2026-02-28) |
BIOCHEMISTRY :PURE AND APPLIED SCIENCES
Markers and Mechanisms of Ageing
Pengalaman / Experience : 12 tahun/years(s)
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
Antioxidants in aging models
Pengalaman / Experience : tahun/years(s)
BASIC MEDICAL SCIENCES :CLINICAL AND HEALTH SCIENCES
C.elegans as an ageing model
Pengalaman / Experience : 12 tahun/years(s)