pensyarah universiti
institut biologi sistem (inbiosis)
clng@ukm.edu.my
Biografi/ Biography :
Dr. Ng Chyan Leong is a senior research fellow in the Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia. He graduated from the Universiti Putra Malaysia where he earned a Bachelor in Biotechnology and Master in Molecular Biology. He completed his PhD in structural biology at the York Structural Biology Laboratory, University of York, UK. He then worked as postdoctoral fellow at the Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK. His researches focus on the structural and functional studies of biologically important macromolecules including secondary metabolites biosynthesis enzymes, hypothetical proteins in human and pathogenic bacteria.
ng chyan leong;sheila nathan;mohd firdaus bin mohd raih;lam su datt. (2025). artificial intelligence predicted 3d structure-guided functional studies towards biochemical characterisation of burkholderia pseudomallei hypothetical proteins. - . .
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
harishaa thangarajan, mohd firdaus mohd raih, sabrina mohamed moffi, doris quay huai xia, lam kok wai, mohd anuar jonet, chyan leong ng. (2024). structural characterization of alternative sites for drug repurposing against antibiotic-resistant bacteria. - asian regional conference on systems biology 2023. 57.
asqwin uthaya kumar, muhammad ahmad zan, chyan-leong ng, sylvia chieng, sheila nathan. (2024). diabetes and infectious diseases with a focus on melioidosis. - current microbiology. 1-14.
neng-yao goh, yeannie hui-yeng yap, chyan leong ng, boon-hong kong, szu-ting ng, chon-seng tan, muhammad fazril mohamad razif, shin-yee fung. (2024). water-soluble compounds from lignosus rhinocerus tm02 (xlr) modulate ace2 activity and inhibit its interaction with sars-cov-2 spike-protein. - food bioscience. 1-15.
neng-yao goh, yeannie hui-yeng yap, chyan leong ng, boon-hong kong, szu-ting ng, chon-seng tan, muhammad fazril mohamad razif, shin-yee fung. (2024). water-soluble compounds from lignosus rhinocerus tm02 (xlr) modulate ace2 activity and inhibit its interaction with sars-cov-2 spike-protein. - food bioscience. 1-15.
rubashiny veeramohan, arief izzairy zamani, kamalrul azlan azizan, hoe-han goh, wan mohd aizat, mohd fauzi abd razak, nur sabrina mohd yusof, sharif mahsufi mansor, syarul nataqain baharum, chyan leong ng. (2023). comparative metabolomics analysis reveals alkaloid repertoires in young and mature mitragyna speciosa (korth.) havil. leaves. - plos one. 1-24.
sofiyah shaibullah; nurshahirah shuhaimi; de-sheng ker; nurhikmah mohd-sharif; kok lian ho; aik-hong the; jitka waterman; thean-hock tang; rui-rui wong; sheila nathan; rahmah mohamed; min jia ng; shin-yee fung; mohd firdaus-raih; chyan leong ng; et. al. (2023). structural and functional analyses of burkholderia pseudomallei bpsl1038 reveal a cas-2/vapd nuclease sub-family. - communications biology. 1-15.
mahasakthy-vijeyasri satyaveanthan, chyan leong ng, alias awang, kok wai lam, maizom hassan. (2023). isolation, purification and biochemical characterization of conopomorpha cramerella farnesol dehydrogenase. - insect molecular biology. 143-159.
tiew-yik ting, anis baharin, ahmad bazli ramzi, chyan-leong ng, hoe-han goh. (2022). neprosin belongs to a new family of glutamic peptidase based on in silico evidence. - plant physiology and biochemistry. 23-35.
asqwin uthaya kumar, muhammad ahmad zan, chyan-leong ng, sylvia chieng, sheila nathan. (2024). diabetes and infectious diseases with a focus on melioidosis. - current microbiology. 1-14.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). biofilm signaling, composition and regulation in burkholderia pseudomallei. - journal of microbiology and biotechnology. 15-27.
juwairiah remali, noraziah mohamad zin, chyan leong ng, wan m. aizat & john j.l tiong. (2019). fenazin sebagai potensi antibiotik baru daripada streptomyces kebangsaanensis. - sains malaysiana. 543-553.
juwairiah remali, kok-keong loke, chyan leong ng, wan mohd aizat, john tiong & noraziah mohamad zin. (2017). whole-genome shotgun sequence of phenazine-producing endophytic streptomyces kebangsaanensis suk12. - genomics data. 7-10.
nurhikmah mohd sharif, sofiyah shaibullah, vasanthakumar givajothi, cheng-seng tan, kok lian ho, aik hong teh, syarul nataqain baharum, jitka waterman & chyan leong ng. (2017). crystallization and x-ray cystallographic analysis of recombinant tylp, a putative gamma-butyrolactone receptor protein from streptomyces fradiae. - acta crystallographica section f-structural biology. 109-115.
asqwin uthaya kumar, muhammad ahmad zan, chyan-leong ng, sylvia chieng, sheila nathan. (2024). diabetes and infectious diseases with a focus on melioidosis. - current microbiology. 1-14.
neng-yao goh, yeannie hui-yeng yap, chyan leong ng, boon-hong kong, szu-ting ng, chon-seng tan, muhammad fazril mohamad razif, shin-yee fung. (2024). water-soluble compounds from lignosus rhinocerus tm02 (xlr) modulate ace2 activity and inhibit its interaction with sars-cov-2 spike-protein. - food bioscience. 1-15.
mahasakthy-vijeyasri satyaveanthan, chyan leong ng, alias awang, kok wai lam, maizom hassan. (2023). isolation, purification and biochemical characterization of conopomorpha cramerella farnesol dehydrogenase. - insect molecular biology. 143-159.
rubashiny veeramohan, arief izzairy zamani, kamalrul azlan azizan, hoe-han goh, wan mohd aizat, mohd fauzi abd razak, nur sabrina mohd yusof, sharif mahsufi mansor, syarul nataqain baharum, chyan leong ng. (2023). comparative metabolomics analysis reveals alkaloid repertoires in young and mature mitragyna speciosa (korth.) havil. leaves. - plos one. 1-24.
sofiyah shaibullah; nurshahirah shuhaimi; de-sheng ker; nurhikmah mohd-sharif; kok lian ho; aik-hong the; jitka waterman; thean-hock tang; rui-rui wong; sheila nathan; rahmah mohamed; min jia ng; shin-yee fung; mohd firdaus-raih; chyan leong ng; et. al. (2023). structural and functional analyses of burkholderia pseudomallei bpsl1038 reveal a cas-2/vapd nuclease sub-family. - communications biology. 1-15.
shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 7.
hoe han goh, chyan leong ng, kok keong loke. (2018). omics applications for systems biology - advances in experimental medicine and biology 1102. - . 19.
shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 7.
chyan leong ng & mohd firdaus-raih. (2019). encyclopedia of bioinformatics and computational biology. - . 14.
hoe han goh, chyan leong ng, kok keong loke. (2018). omics applications for systems biology - advances in experimental medicine and biology 1102. - . 19.
ng chyan leong;sheila nathan;mohd firdaus bin mohd raih;lam su datt. (2025). artificial intelligence predicted 3d structure-guided functional studies towards biochemical characterisation of burkholderia pseudomallei hypothetical proteins. - . .
hamizah shahirah binti hamezah;syarul nataqain binti baharum;wan mohd aizat bin wan kamaruddin;ng chyan leong. (2024). elucidating the effect of mitragynine supplementation on brain proteome profiles, cognitive and locomotor functions of lipopolysaccharide-induced neuroinflammation in rats. - . .
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2024). structural and functional characterisation of the burkholderia pseudomallei biofilm biosynthesis-related hypothetical protein bpsl0610. - asian regional conference on systems biology 2023. 46.
harishaa thangarajan, mohd firdaus mohd raih, sabrina mohamed moffi, doris quay huai xia, lam kok wai, mohd anuar jonet, chyan leong ng. (2024). structural characterization of alternative sites for drug repurposing against antibiotic-resistant bacteria. - asian regional conference on systems biology 2023. 57.
sylvia chieng;ng chyan leong. (2024). burkholderia pseudomallei biofilm extracellular polymeric proteins as potential targets for inhibitor design. - . .