Biografi/ Biography :
My research is primarily directed at understanding molecular function regulation by exploring the mechanistic atomic level interactions that affect function and/or effect molecular level switching as well as the associated regulatory pathways. To accomplish this, my research group studies the structure, function and evolution of biological macromolecules to compare how the atomic level differences can result in different functions by effecting regulatory or mechanistic changes. We source our data from public repositories such as GenBank and the Protein Data Bank as well as by generating internal data such as genome sequences, transcriptome sequences and methylome sequences from specific experiments. The approaches employed in exploring and investigating these datasets primarily involve bioinformatics, computational biology and genomics but also extend to structural biology (mainly X-ray crystallography), synthetic biology and systems biology. The insights revealed from these investigations can provide clues as to how molecular level regulation and responses in living systems are carried out that eventually lead to an organism’s capacity to adapt to extreme (ie. extremophiles) or diverse environments (ie. such as a bacterial pathogen or parasite adapting to a host) as well as the discovery of novel factors associated with pathogenesis (toxins and pathogenesis/virulence regulation systems). Our understanding of the atomic level interactions that define specific biological mechanisms have led to the development of applications for drug repositioning and tools for the synthetic design of nucleic acid self-assembling structures.
nur khairun atiyah sagee ahmad, balqis az-zahraa norizan, doris huai xia quay, mohd firdaus raih and sharifah nabihah syed jaafar. (2025). enhancement of lysozyme physicochemical stability and biocatalytic activity through direct electrostatic complexation with cellulose nanospheres. - carbohydrate polymers. 123957 - 123968.
ashraf attia mahmoud, mohd firdaus raih, edison eukun sage, qurashi m. ali, omnia h. suliman, sabah a. e. ibrahim, osama mohamed, samar abdelrazeg, sofia b. mohamed. (2025). the impact of mutations on tp53 protein and microrna expression in hnscc: novel insights for diagnostic and therapeutic strategies. - plos one. 1 - 21.
roslan abd shukor, mohd firdaus mohd raih, muhammad yahaya, azman jalar. (2025). 50 tahun meneroka alam: jabatan fizik universiti kebangsaan malaysia 1970-2020. - . .
cecilia paradiso, paolo gratton, emiliano trucchi, julia lópez-delgado, marco gargano, lorenzo garizio, ian m carr, giuliano colosimo, christian sevilla, mark e welch, mohd firdaus-raih, mohd noor mat-isa, simon j goodman, gabriele gentile. (2025). genomic insights into the biogeography and evolution of galápagos iguanas. - molecular phylogenetics and evolution. 1 - 13.
razik ridzuan mohd tajuddin, noriszura ismail, mohammad rahim kamaluddin, ahmad azwan amin nordin, mohd firdaus-raih. (2025). imbalance in spatiotemporal analysis of narcotics-related activities: a bibliometric review. - humanities and social sciences communications. 1 - 13.
cecilia paradiso, paolo gratton, emiliano trucchi, julia lópez-delgado, marco gargano, lorenzo garizio, ian m carr, giuliano colosimo, christian sevilla, mark e welch, mohd firdaus-raih, mohd noor mat-isa, simon j goodman, gabriele gentile. (2025). genomic insights into the biogeography and evolution of galápagos iguanas. - molecular phylogenetics and evolution. 1 - 13.
razik ridzuan mohd tajuddin, noriszura ismail, mohammad rahim kamaluddin, ahmad azwan amin nordin, mohd firdaus-raih. (2025). imbalance in spatiotemporal analysis of narcotics-related activities: a bibliometric review. - humanities and social sciences communications. 1 - 13.
jialin yin, vaishali p. waman, neeladri sen, mohd firdaus-raih, su datt lam, christine orengo. (2025). understanding the structural and functional diversity of atp-ppases using protein domains and functional families in the cath database. - structure. 613 - 631.
ashraf attia mahmoud, mohd firdaus raih, edison eukun sage, qurashi m. ali, omnia h. suliman, sabah a. e. ibrahim, osama mohamed, samar abdelrazeg, sofia b. mohamed. (2025). the impact of mutations on tp53 protein and microrna expression in hnscc: novel insights for diagnostic and therapeutic strategies. - plos one. 1 - 21.
nur khairun atiyah sagee ahmad, balqis az-zahraa norizan, doris huai xia quay, mohd firdaus raih and sharifah nabihah syed jaafar. (2025). enhancement of lysozyme physicochemical stability and biocatalytic activity through direct electrostatic complexation with cellulose nanospheres. - carbohydrate polymers. 123957 - 123968.
nik yusnoraini yusof, doris huai xia quay, shazilah kamaruddin, mohd anuar jonet, rosli md illias, nor muhammad mahadi, mohd firdaus-raih, farah diba abu bakar, abdul munir abdul murad. (2024). biochemical and in silico structural characterization of a cold-active arginase from the psychrophilic yeast, glaciozyma antarctica pi12. - extremophiles. 1 - 13.
nurul fadzillah fadhar, pravin kumran nyanasegran, mohd firdaus-raih, sheila nathan, mohd anuar jonet, chyan leong ng. (2024). protein expression, purification, crystallization and crystallographic studies of bpsl0741 from burkholderia pseudomallei. - structural biology communications. 263 - 268.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). biofilm signaling, composition and regulation in burkholderia pseudomallei. - journal of microbiology and biotechnology. 15-27.
hafizzudin-fedeli, m., abu-bakar, m.-f., mat-isa, m.-n., latiff, a., firdaus-raih, m., wan, k.-l.. (2022). characterisation of tetrastigma rafflesiae mitochondrial genes and assessment of their potential as sequence markers. - sains malaysiana. 2435-2447.
siti asmaa mat jusoh, danesh thangeswaran, muhammad syahir hakimi mohd hazli, mohd firdaus raih, nurulasma abdullah, shaharum shamsuddin. (2022). construction of multi-epitopes vaccine candidate against sars-cov-2 d614g variant. - sains malaysiana. 2985-2997.
nur khairun atiyah sagee ahmad, balqis az-zahraa norizan, doris huai xia quay, mohd firdaus raih and sharifah nabihah syed jaafar. (2025). enhancement of lysozyme physicochemical stability and biocatalytic activity through direct electrostatic complexation with cellulose nanospheres. - carbohydrate polymers. 123957 - 123968.
cecilia paradiso, paolo gratton, emiliano trucchi, julia lópez-delgado, marco gargano, lorenzo garizio, ian m carr, giuliano colosimo, christian sevilla, mark e welch, mohd firdaus-raih, mohd noor mat-isa, simon j goodman, gabriele gentile. (2025). genomic insights into the biogeography and evolution of galápagos iguanas. - molecular phylogenetics and evolution. 1 - 13.
razik ridzuan mohd tajuddin, noriszura ismail, mohammad rahim kamaluddin, ahmad azwan amin nordin, mohd firdaus-raih. (2025). imbalance in spatiotemporal analysis of narcotics-related activities: a bibliometric review. - humanities and social sciences communications. 1 - 13.
jialin yin, vaishali p. waman, neeladri sen, mohd firdaus-raih, su datt lam, christine orengo. (2025). understanding the structural and functional diversity of atp-ppases using protein domains and functional families in the cath database. - structure. 613 - 631.
ashraf attia mahmoud, mohd firdaus raih, edison eukun sage, qurashi m. ali, omnia h. suliman, sabah a. e. ibrahim, osama mohamed, samar abdelrazeg, sofia b. mohamed. (2025). the impact of mutations on tp53 protein and microrna expression in hnscc: novel insights for diagnostic and therapeutic strategies. - plos one. 1 - 21.
intan azlinda ramlee, mohd firdaus-raih & kiew-lian wan. (2015). identification and characterization of secreted proteins in eimeria tenella. - aip conference proceedings. 030023.
siuk-mun ng, xin-wei lee, kiew-lian wan & mohd firdaus-raih. (2015). comparative differential gene expression analysis of nucleus-encoded proteins for rafflesia cantleyi against arabidopsis thaliana. - the 2015 ukm fst postgraduate colloquium. 030020(1-6).
noor munyati othman, ahmad luqman abdul fatah, mohd al akmarul fizree bin md piji, effirul ikhwan ramlan and mohd firdaus raih. (2015). identification and cloning of four riboswitches from burkholderia pseudomallei strain k96243. - the 2015 ukm fst postgraduate colloquium. 1-5.
nur syamimi yusoff, nadzirah damiri, mohd firdaus-raih. (2014). identification of the conserved hypothetical protein bpsl0317 in burkholderia pseudomallei k96243. - aip conference proceeding - the 2014 ukm fst postgraduate colloquium. 544-548.
naif h. al-hardan, muhammad azmi abdul hamid, chaker tlili, azman jalar, mohd firdaus raih, naser m. ahmed. (2024). gallium oxide uv sensing in contemporary applications. - . 311-336.
shuhaila mat-sharani, doris hx quay, chyan l ng & mohd firdaus-raih. (2019). structural genomics. - . 722-728.
chyan leong ng & mohd firdaus-raih. (2019). applications of ribosomal rna sequence and structure analysis for extracting evolutionary and functional insight. - . 554-567.
munyati othman, siuk m ng, mohd firdaus-raih. (2018). computational design and experimental implementation of synthetic riboswitches and riboregulators. - . 568-573.
suhaila sulaiman, nur s yusoff, ng s mun, haslina makmur, mohd firdaus-raih. (2018). inference of horizontal gene transfer: gaining insights into evolution via lateral acquisition of genetic material. - . 953-964.
su datt lam, doris quay huai xia dan mohd firdaus mohd raih. (2025). peranan bioinformatik struktur dalam menangani wabak baru. - dewan kosmik. .
roslan abd shukor, mohd firdaus mohd raih, muhammad yahaya, azman jalar. (2025). 50 tahun meneroka alam: jabatan fizik universiti kebangsaan malaysia 1970-2020. - . .
rahmah mohamed, rohana yusof, abdul razak m. isa, salmaan hussain inayat hussain, ibrahim abu ahmad, zanariah ahmad, rosli md. illias, norzulaani khalid, mohd firdaus mohd raih. (2022). dasar bioteknologi kebangsaan 2.0. - . 48.
faridah hani mohamed salleh, suhaila zainudin,mohd firdaus raih. (2021). model regresi untuk pembinaan semula rangkaian pengawal atur gen. - . 162.
mohd firdaus mohd raih. (2020). masyarakat celik sains menjadi faktor penentu kemenangan menentang covid-19. - majalahsains.com. 1-6.
su datt lam, doris quay huai xia dan mohd firdaus mohd raih. (2025). peranan bioinformatik struktur dalam menangani wabak baru. - dewan kosmik. .
saiful irwan zubairi, mohd firdaus mohd raih. (2024). ukm fst and tuah herbology team up for nutraceutical and cosmetic research. - sinar daily (sinar harian english version) - focus (national) section. 1-3.
harishaa thangarajan, mohd firdaus mohd raih, sabrina mohamed moffi, doris quay huai xia, lam kok wai, mohd anuar jonet, chyan leong ng. (2024). structural characterization of alternative sites for drug repurposing against antibiotic-resistant bacteria. - asian regional conference on systems biology 2023. 57.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2024). structural and functional characterisation of the burkholderia pseudomallei biofilm biosynthesis-related hypothetical protein bpsl0610. - asian regional conference on systems biology 2023. 46.
pravin kumran nyanasegran, sheila nathan, mohd firdaus raih, nor azlan nor muhammad, chyan leong ng. (2023). characterisation of the beca-r gene cluster involved in the synthesis of burkholderia pseudomallei biofilm exopolysaccharide. - "joint 11th asia oceania human proteome organization (aohupo) and 7th asia oceania agricultural proteomics organization (aoapo) congress". 309.